Miranti CK, Brugge JS: Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 2002, 4 (4) : E83–90.CrossRefPubMed 3. Hughes selleck compound PE, Pfaff M: Integrin affinity modulation. Trends Cell Biol 1998, 8 (9) : 359–364.CrossRefPubMed 4. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR: Cell migration: integrating signals from front to back. Science 2003, 302 (5651) : 1704–1709.CrossRefPubMed 5. Miyamoto S, Akiyama SK, Yamada KM: Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 1995, 267 (5199) : 883–885.CrossRefPubMed
6. Stewart MP, McDowall A, Hogg N: LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain. J Cell Biol 1998, 140 (3) : 699–707.CrossRefPubMed 7. van Kooyk Y, van Vliet SJ, Figdor CG: The actin cytoskeleton LEE011 regulates LFA-1 ligand binding through avidity rather than affinity changes. J Biol Chem 1999, 274 (38) : 26869–26877.CrossRefPubMed
8. Schwartz MA, Ginsberg MH: Networks and crosstalk: integrin signalling spreads. Nat Cell Biol 2002, 4 (4) : E65–68.CrossRefPubMed 9. Miyamoto S, Teramoto H, Gutkind JS, Yamada KM: Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J Cell Biol 1996, 135 (6 Pt 1) : 1633–1642.CrossRefPubMed 10. Shaw LM: Integrin function in breast carcinoma progression. J Mammary Gland Biol Neoplasia 1999, 4 (4) : 367–376.CrossRefPubMed 11. Perou CM, Sorlie T, Eisen MB, Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D: Molecular portraits of human breast tumours. Nature 2000, 406 (6797) : 747–752.CrossRefPubMed 12. Rabinovitz I, Toker A, Mercurio AM: Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions
drive the chemotactic migration of carcinoma cells. J Cell Biol 1999, 146 (5) : 1147–1160.CrossRefPubMed Ponatinib 13. Mariotti A, Kedeshian PA, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG: EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol 2001, 155 (3) : 447–458.CrossRefPubMed 14. Mainiero F, Pepe A, Yeon M, Ren Y, Giancotti FG: The intracellular functions of alpha6beta4 integrin are regulated by EGF. J Cell Biol 1996, 134 (1) : 241–253.CrossRefPubMed 15. Peterson EJ, Woods ML, Dmowski SA, Derimanov G, Jordan MS, Wu JN, Myung PS, Liu QH, Pribila JT, Freedman BD, Shimizu Y, Koretzky GA: Coupling of the TCR to integrin activation by Slap-130/Fyb. Science 2001, 293 (5538) : 2263–2265.CrossRefPubMed 16.