Table 1 The demographic and baseline hemodynamic data (mean±SD) of patients

in the control and experiemntal groups Table 2 Heart rate (beats/min) of the experimental and control groups during the operation and in recovery room Table 3 Comparison of systolic and diastolic blood pressures of the experimental and control groups during the operation and in recovery room No patient in the two groups experienced transient neurological symptoms. The highest level of sensory block in all patients was T4. Moreover, the time to reach maximum sensory extension was not significantly (p value=0.002) different between the two groups. Duration of maximum sensory block to regress Inhibitors,research,lifescience,medical to L1 was significantly (P<0.0001) different between the two groups. Duration of complete motor block was not different between the two groups (P =0.82). The mean duration Inhibitors,research,lifescience,medical of analgesia in the control group was 88.89 minutes while in the experimental group was 137.28 minutes. The difference of analgesia duration in the two study groups was statistically significant (P<0.0001) (table 4). There was no significant difference (P>0.05) between the size and volume of prostate between the control and experimental groups. Table 4 Analgesia characteristics of experimental and control groups The incidence of ZVADFMK hypotension (more than 30% decrease in SBP), which required ephedrine administration, in the experimental Inhibitors,research,lifescience,medical group

was 18.4% and in the control group was 66.7%.The incidence of nausea and vomiting in the experiment group was 23.7% and in the control group was 5.1%.The incidence of pruritus in the control group was 0% and in the experimental group was 12.8%.The two groups were only significantly (P<0.0001) different in terms of hypotension and Inhibitors,research,lifescience,medical ephedrine use, but not the incidence of nausea, vomiting or pruritis. The incidence of the needs to analgesia

in the experimental group (10.5%) was insignificantly (P=0.22) lower than that of the control group (23.1%). However, Inhibitors,research,lifescience,medical the incidence of shivering in the control group (2.6%) was insignificantly less than that in experimental group (17.9%) (table 5). No patient in the two groups experienced respiratory depression and no individual needed mask ventilation. There was significant difference in the changes (decrease) of hemoglobin concentration (p <0.001) or blood loss (P<0.001) first of the experimental and control groups. The transfusion rate in the experimental group (13.2%) was half of that of the experimental group (25.6%). Moreover, the transfusion rate or post-operation hemoglobin was not statistically significant between the two groups. Moreover, no significant (P>0.05) difference was found between the size or volume of prostate in the control and experimental groups. Table 5 The number and percentage of side effects occurred in experimental and control groups Discussion This study revealed that adding 0.