Gene Category: List EASE score Bev lkerung bootstrap level of gene expression. Contr Vs UNBS5162 to the sum total of the requests 10 M 1 M mount biological process nucleosomes 11 75 56 10 401 5 10 2 .001 × � H2AFY 2, 6 0.3 0.3 NA NA NA HIST1H3H LY317615 Enzastaurin HIST1H2BD chromatin Assembly / Disassembly CXCL8 CXCL11, 0 1.8 1.0 4.8 1.1 2.9 4.2 2.1 CXCL10 CXCL5 system refers to the categorization system genes in the databases by the ease software package made available. Gene category refers to the specific class of genes within the system. Visits List refers to the number of genes in the list of differentially expressed genes, the genes of the class go Ren. List refers to the total number of genes in a list of differences that are a class of gene in the system.
Visit the Bev Lkerung is the number of genes in the entire group of genes tested, the category-specific gene go Ren. Bev Lkerung Brivanib refers to a number of genes in the list, to a previous category go Ren genes within the system. The EASE score is the probability value of the change in the proportion between the two ratios: the hits of the Bev lkerung / lkerung total population and the list of hits / total number of lists. It is the upper band of the distribution of p Fisher exact calculations on a probability based on a ratio of these two Ratios. The bootstrap method is an iterative analysis ��berrepr Presentation, on the lists of genes at random, to determine more accurately the true probability. NA = not available because it is an overlap between the two intervals. Reference state corresponds to results of EASE.
Flight neoplasia. 10, No. 6, 2008 naphthalimide and treatment of prostate cancer Mijatovic et al. 583 Figure 5 UNBS5162 induced alignment of the CXCL chemokines and the effects on angiogenesis. The relative expression levels of mRNA for CXCL chemokines in untreated and treated UNBS5162 PC 3 cells as assessed by analyzing the entire microarray. Data are presented as means �� SEM. UNBS5162 in vivo anti-angiogenic effects after repeated administration of 10 mg / kg iv Mice With orthotopic PC 3 xenografts induced implanted. UNBS5162 mediated reduction of angiogenesis in this model was subsequently by Z Select blood vessels E in histological sections of excised tumors End with H Matoxylin and eosin found Quantified prepared rabbit.
Ten measurements per sample were performed and the results are expressed as a percentage of the Fl Surface of blood vessels S from M UNBS5162 treated Mice compared to untreated control aids Mice erfa-run. Data are presented as means �� SEM. Films represent untreated distant tumors and tumors of animals treated UNBS5162 to F Staining with H Matoxylin and eosin for Z Select blood vessels E cut. ELISA determination of CXCL1 and CXCL8 protein in treated and 5 M 1 UNBS5162 treated PC 3 and DU-145 cells. Were treated in experiments UNBS5162 were collected to whichever type Walls 24 and 72 hours after the last treatment. The concentrations of two specific chemo