Prognosis is severe in children, especially in those with age less than 1 year or severe malnutrition.[1] Adult mortality rates are also high in immunocompromised patients.[3, 6] Conversely, elderly patients without underlying disease and young immune-competent

adults are much more likely to have a favorable outcome,[4, 5, 7] as observed in our two patients. Shigellosis, because of its severity, should always be treated, whether bacteremia is found or not. But the global increase in antibiotic resistance limits the choice of drugs.[1] Among Dasatinib order recommended treatments, fluoroquinolones or third-generation cephalosporins are the best choices for Shigella bacteremias, but sensitivity must be confirmed. Due to an absence of controlled studies, there is no consensus on treatment duration. Courses generally range between 5 and 14 days, depending on the severity and duration of symptoms.[3-5] Shigella bacteremia is fortunately uncommon in healthy travelers. When an underlying disease is absent, it should alert the physician to the possibility

of a transient co-morbid condition. These case reports underline the importance for travelers to seek pre-travel advice and be prepared to prompt self-treatment of diarrhea with an antibiotic-containing regimen. The authors thank Dr M. Nesemann for linguistic assistance. The authors state they have no conflicts of interest to declare. “
“Clinical and laboratory findings are described from 77 persons from Nairobi, Kenya, of whom 66 Epigenetic inhibition acetylcholine were diagnosed with acute Schistosoma mansoni infection following a trip to Mwanza, Tanzania. Unusual ocular symptoms were observed as a rare manifestation of acute schistosomiasis. The outbreak highlights

the risk of swimming in Lake Victoria. In August 2008, the Seventh Day Adventist (SDA) group of churches in East Africa organized a family retreat to Mwanza in Tanzania, located on the shores of Lake Victoria. They were there for several days, during which most of them swam in the lake, having been assured that the water was “safe.” Once the retreat was over, the families returned to their homes all over the East African region and beyond. Approximately 8 weeks after exposure to the lake water, on October 28, 2008, a 10-year-old girl was referred to the Centre for Tropical and Travel Medicine (CTTM) laboratory for malaria and hemoglobin testing. The child presented with general malaise which her mother thought was malaria, but she also had periorbital edema. On examination of the Giemsa-stained blood slide, marked eosinophilia was noted in the absence of malaria. Given the history of recent swimming in Lake Victoria during the church retreat to Mwanza, a blood test for bilharzia antibody was requested, which was positive at a titer of 1 : 1024. The child was put on treatment with praziquantel at a dose of 40 mg/kg daily for 4 days, and her symptoms subsided rapidly.