ABO-incompatible KT can be a valuable option for expanding donor pool. Spouses are an important source of living donors as kidney donors in a worldwide. This study was to compare the clinical outcomes of ABO-compatible (ABOc) and ABO-incompatible
(ABOic) KT from spousal donors. Methods: From January 2011 to August 2013, the recipients who underwent KT from spousal donors were enrolled. We investigated patient survival, graft survival, graft function, acute rejection, and complications. Results: Among 32 spousal donors KT, 21 cases were ABOc KTs and 11 were ABOic KTs. The mean recipient ages were 50.9 and 49.0 years, respectively. The mean donor ages were 49.3 and 47.6 years. The mean follow up durations were 15 ± 7.7 and 15 ± 8.0 months. During follow up duration, there was no patient and graft loss in both groups. There were no significant differences in the incidence of delayed graft function and acute rejection. Mean serum creatinine
at buy SCH772984 1 year after KT were 1.3 ± 1.31 mg/dL and 1.2 ± 0.42 mg/dL, respectively. The incidence of infection such as cytomegalovirus, other virus, bacteria and fungus between the two groups were no significant differences. Conclusion: The clinical outcomes of ABOic KTs were not inferior compare with ABOc KTs in KT from spousal donors. In ABOic KT, an emotionally motivated spousal donor KT may be a good alternative to solve the problem that is the absolute shortage of kidney donor. HUNG KUAN-YU1, HUANG JENQ-WEN1, LIN CHIA-KUEI2, CHIANG CHIH-KANG1 1Department of Nephrology,
National Taiwan University Hospital (NTUH); 2Center for Quality Management, NTUH Introduction: Morbidity and mortality screening assay conference (MMC) Glycogen branching enzyme provides clinicians an opportunity to discuss disease, medical error and adverse events. However, there is less learning points or improvement actions implemented in traditional MMCs. To promote patient safety and educational effectiveness, we implemented a monthly multi-disciplinary MMC at our dialysis unit. Methods: An independent task force evaluate educational effectiveness of this new format of MMC. Two well-trained, quality and safety managers of this task force attended the MMCs for collecting data on case presentation, discussion between attendees, cause-and-effect of the event, and learning points or improvement actions to prevent its occurrence. We measured perceptions, learning feedbacks from participants by using anonymous questionnaires. Results: Eleven MMCs involving 20 participants and 84 cases were studied from February 2013 to December 2013. These events included unexpected deaths (8%), prolonged infection management (25%), PD technique failure (32%), and procedural complications (35%). The most common factors leading to these events were inadequate coordination in patient care (75%), and in almost (88%) all 84 cases, individual contributing factors can be retrospectively identified and can be transformed into improvement actions.