77% in terms of compression ratio.”
“Background: The present cross-sectional study evaluates the utility of the Composite Index of Anthropometric Failure (CIAF) over conventional nutritional indices for nutritional assessment. It also assesses the impact of various socio-economic and demographic factors on the CIAF.\n\nSubjects and methods: Height, weight, Selleck QNZ age, socio-economic and demographic data were recorded from 3444 children (1682 boys; 1762 girls)

aged 1-12 years and residing in Darjeeling district, West Bengal, India. The conventional anthropometric indices and CIAF were compared with the NCHS reference data to assess prevalence of under-nutrition. A multinomial logistic regression was used to assess the impact of different socio-economic and demographic variables on

the CIAF.\n\nResults: Prevalence of under-nutrition was observed to be 21.5% (wasting), 43.3% (stunting) and 52.0% (underweight). This increased to 63.6% using the CIAF. The multinomial logistic regression odds showed that children suffering from double and multiple failures were significantly associated with the socio-economic and demographic variables.\n\nConclusion: The CIAF provides more precision in identifying the nutritionally vulnerable segment of the population. The disaggregation of CIAF has an adequate potential to enhance the efficacy of a nutritional intervention programme by identifying double or multiple failures.”
“The study of mechanisms by which animals tolerate environmental selleck chemicals llc extremes may provide strategies for preservation of living Luminespib in vivo mammalian materials. Animals employ a variety of compounds to enhance their survival, including production of disaccharides, glycerol, and antifreeze compounds. The cryoprotectant glycerol was discovered before its role in amphibian survival. In the last decade, trehalose has made an impact on freezing and drying methods for mammalian cells. Investigation of disaccharides was stimulated by the variety of

organisms that tolerate dehydration stress by accumulation of disaccharides. Several methods have been developed for the loading of trehalose into mammalian cells, including inducing membrane lipid-phase transitions, genetically engineered pores, endocytosis, and prolonged cell culture with trehalose. In contrast, the many antifreeze proteins (AFPs) identified in a variety of organisms have had little impact. The first AFPs to be discovered were found in cold water fish; their AFPs have not found a medical application. Insect AFPs function by similar mechanisms, but they are more active and recombinant AFPs may offer the best opportunity for success in medical applications. For example, in contrast to fish AFPs, transgenic organisms expressing insect AFPs exhibit reduced ice nucleation.