3 months. Within follow-up periods, gallstone formations occurred in 108 of 1,527 (7.1%) patients. Cumulative gallstone formation occurred in 37 (34.3%), 56 (51.9%), and 90 (83.3%) patients within 1, 2 and 5 years after surgery. On univariate Cox regression analysis, age (HR 1.03; 95% CI, 1.01–1.05), male sex (HR 2.18; 95% CI, 1.35–3.51), postoperative body mass index <23 kg/m2 (HR 1.54; 95% CI, 1.05–2.26), and subtotal gastrectomy with Billroth II anastomosis or total gastrectomy (HR 1.60 or 2.41; 95% CI, 1.02–2.52 or 1.51–3.86) were associated with gallstone formation. On multivariable Cox regression analysis, age (HR 1.03; 95% CI,

1.01–1.05), male sex (HR 1.98; 95% CI, 1.23–3.21), postoperative body mass index <23 kg/m2 (HR 1.54; 95% CI, 1.05–2.26), and total gastrectomy (HR 2.27; 95% CI, 1.41–3.65) remained significantly associated with gallstone formation. Only nine (0.6%) patients experienced symptomatic AZD4547 datasheet cholecystitis and there was no difference

according to variables. Conclusion: The risk of gallstone formation increased according to age, male sex, postoperative decreased body mass index (<23 kg/m2), and total gastrectomy. Unlike previous studies that documented gallstones mostly occur within first two years after gastrectomy, gallstones were learn more found even after 2 years of surgery. Considering lower risk of cholecystitis after gastrectomy, prophylactic cholecystectomy should not be recommended. MCE Key Word(s): 1. gastric cancer; 2. gastrectomy; 3. gallstone; 4. cholecystitis

Presenting Author: TAE YOUNG PARK Additional Authors: SUNG KOO LEE, JIN SEOK PARK, DONGWOOK OH, TAE JUNE SONG, DO HYUN PARK, SANG SOO LEE, DONG WAN SEO, MYUNG HWAN KIM Corresponding Author: TAE YOUNG PARK Affiliations: Asan Medical Center, Asan Medical Center, Asan Medical Center, Asan Medical Center, Asan Medical Center, Asan Medical Center, Asan Medical Center, Asan Medical Center Objective: Biliary complications are major cause of morbidity in liver transplantation (LT) patients. Among various LT-related complications, spontaneous hemobilia is infrequent, but can lead to graft dysfunction such as obstructive jaundice and cholangitis by clots. The etiology and mechanism of spontaneous hemobilia after LT has not been well elucidated. The aim of this retrospective study is to assess risk factor of spontaneous hemobilia after LT Methods: LT patients with endoscopically confirmed hemobilia without history of liver biopsy from January 2006 to April 2014 were enrolled to case group (n = 33). 1:2 age and sex matched LT patients without hemobilia were enrolled to control group (n = 66). To evaluate risk factor of spontaneous hemobilia, clinical data were collected and logistic regression analysis was performed. Results: Thirty three patients in case group (male 24, 72.7%; mean age, 52.4 ± 8.7 years) and 66 patients in control group (male 48, 72.7%; mean age, 52.2 ± 8.5 years) were analyzed.