were performed four times. Mean values of the four repetitions, standard deviations, and CV were calculated and the mean value was considered the value which was then used to categorize the isolates as “R”, “I” or “S”. The susceptibility profile of mucoid and non-mucoid isolates was evaluated under the different conditions performed in this study (MIC, BIC and MCA). Statistical analysis The Wilcoxon signed ranks test was used for statistical analysis of quantitative values of MIC and BIC. McNemar-Bowker test was used to evaluate the categories Dinaciclib of the results obtained (“S”, “I” and “R”) by the standard technique and the technique in biofilm. P < 0.05 indicated statistical Selleckchem Ilomastat significance.
Ethics aspects The bacterial isolates were obtained from clinical specimens sent for routine culture in the Microbiology Unit of Hospital de Clínicas de Porto Alegre. The information was compiled in order to Talazoparib purchase respect the privacy of patients; written informed consent for participation in the study was obtained from participants or, where participants were children, from a parent or guardian. This study was approved by the Ethics Committee in Research of Hospital de Clínicas de Porto Alegre (project number 06 – 406). Acknowledgements We would like to thank Vania Naomi Hirakata for assistance O-methylated flavonoid with statistical analyses. Funding This work received financial support from FIPE (Fundo de Incentivo à Ensino e Pesquisa do Hospital de Clínicas de Porto Alegre), CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) and ANVISA (Agência Nacional de Vigilância Sanitária). References 1. Staab D: Cystic fibrosis – therapeutic challenge in cystic fibrosis children. Eur J Endocrinol 2004,151(Suppl 1):S77-S80.PubMedCrossRef 2. Baltimore RS, Christie CD, Smith GJ:
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