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“Natural rubber (NR) of grade RSS4 was efficiently cured (crosslinked) by using sulfur: accelerator weight ratio of 1 : 4. This was further compounded with high abrasion grade carbon black filler (grade JNJ-26481585 N330) with three different doses, that is, 5,

10, and 20 wt % of rubber to form three different filled and crosslinked membranes designated as NR5, NR10, and NR20, respectively. These filled rubber membranes and one unfilled but efficiently cured membrane, that is, NR0, were used for pervaporative removal of low concentration of pyridine from water. The filled membranes were found to show higher pyridine selectivity but lower flux than the unfilled membrane. All of these membranes showed reasonably good range of flux and pyridine selectivity. Among all of the used membranes, NR5-filled membrane yielded high pyridine selectivity (122) with reasonable thickness normalized flux (2.2 kg m-2 h-1 m mu) at 40 degrees C for 0.5 wt % of pyridine in water. AZD9291 mouse (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012″
“Ovarian

cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well advanced. Overall 5-year survival is a rather dismal 50% but can be improved to greater than 90% if the disease is confined to the ovary at the time of diagnosis (generally in fewer than 25% of patients). Effective screening tools are currently not available. Owing to the rather low incidence of the disease in the general population, potential screening tests must provide very high specificity to avoid unnecessary interventions in false-positive cases. This article reviews currently available serum biomarkers and imaging tests for the early detection of ovarian cancer and provides an outlook on the potential improvements in these noninvasive diagnostic tools that may lead to successful implementation in a screening program. (C) RSNA, 2011″
“The dense granule protein 4 (GRA4) is a granular protein from Toxoplasma gondii, and is a candidate for vaccination against this parasite. In this study, the plasmid pcDNA3.1-GRA4 (pGRA4), encoding for the GRA4

https://www.selleckchem.com/products/VX-765.html antigen, was incorporated by the dehydration-rehydration method into liposomes composed of 16 mmol/L egg phosphatidylcholine (PC), 8 mmol/L dioleoyl phosphatidylethanolamine (DOPE), and 4 mmol/L 1,2-diodeoyl-3-(trimethylammonium) propane (DOTAP). C57BL/6 mice and BALB/c mice were immunized intramuscularly three times with liposome-encapsulated pGRA4 to determine whether DNA immunization could elicit a protective immune response to T. gondii. Enzyme-linked immunosorbent assay (ELISA) of sera from immunized mice showed that liposome-encapsulated pGRA4 generated high levels of IgG antibodies to GRA4. Production of primary interferon (IFN)-gamma and interleukin (IL)-2 in GRA4-stimulated splenocytes from vaccinated mice suggested a modulated Th1-type response. 72.