Cancer Res 2006, 66:3639–3648 PubMedCrossRef 11 Gaustad JV, Simo

Cancer Res 2006, 66:3639–3648.PubMedCrossRef 11. Gaustad JV, Simonsen TG, Leinaas MN, Rofstad EK: Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts. BMC Cancer 2012, 12:388.PubMedCrossRef

12. Yankeelov TE, Arlinghaus LR, Li X, Gore JC: The role of magnetic resonance imaging biomarkers in clinical trials of treatment response in cancer. Semin Oncol 2011, 38:16–25.PubMedCrossRef 13. Padhani AR: Diffusion magnetic resonance imaging in cancer patient management. Semin Radiat Oncol 2011, 21:119–140.PubMedCrossRef 14. Batchelor TT, Duda DG, di Tomaso E, Ancukiewicz M, Plotkin SR, Gerstner E, Eichler AF, Drappatz J, Hochberg FH, Benner T, et al.: Phase II study of cediranib, an oral pan-vascular

endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent Selleck Idasanutlin glioblastoma. J Clin Oncol 2010, 28:2817–2823.PubMedCrossRef 15. Loveless ME, Lawson D, Collins M, Nadella MV, Reimer C, Huszar D, Selleck S63845 Halliday J, Waterton JC, Gore JC, Yankeelov TE: Comparisons of the efficacy of a Jak1/2 inhibitor this website (AZD1480) with a VEGF signaling inhibitor (cediranib) and sham treatments in mouse tumors using DCE-MRI, DW-MRI, and histology. Neoplasia 2012, 14:54–64.PubMed 16. Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HB, Lee TY, Mayr NA, Parker GJ, et al.: Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999, 10:223–232.PubMedCrossRef 17. Tofts PS: Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. J Magn Reson Imaging 1997, 7:91–101.PubMedCrossRef 18. Egeland TA, Simonsen TG, Gaustad JV, Gulliksrud K, Ellingsen C, Rofstad EK: Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images. Radiat Res 2009,

172:339–347.PubMedCrossRef 19. Roskoski R Jr: Sunitinib: a VEGF and PDGF receptor protein kinase and angiogenesis inhibitor. Biochem Biophys Res Commun 2007, 356:323–328.PubMedCrossRef 20. Demetri GD, van Oosterom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, McArthur G, Judson IR, Heinrich MC, Morgan JA, et al.: Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure ASK1 of imatinib: a randomised controlled trial. Lancet 2006, 368:1329–1338.PubMedCrossRef 21. Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, Negrier S, Szczylik C, Pili R, Bjarnason GA, et al.: Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 2009, 27:3584–3590.PubMedCrossRef 22. Raymond E, Hammel P, Dreyer C, Maatescu C, Hentic O, Ruszniewski P, Faivre S: Sunitinib in pancreatic neuroendocrine tumors. Target Oncol 2012, 7:117–125.PubMedCrossRef 23.

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