You will find at least three reasons including making proof for clinical logical use scientifically, building a goal and transparent identifying strategy, eventuating and showcasing its clinical price. The process and approach to wellness technology assessment(HTA) can provide reference when it comes to organization of extensive assessment method of Chinese patent medicine. But, HTA is rarely done in the field of standard Chinese medicine. The latest domestic and international study revealed that HTA along with multi-criteria decision analysis(MCDA) can increase the transparency of decision-making and enhance the high quality of decision-making. The combined two formed the EVIDEM framework, that will be favorable to medicine choice and its medical usage. In this paper, the EVIDEM framework had been introduced to determine the methodology framework associated with the comprehensive clinical analysis system of Chinese patent medicine. A preliminary research concept happens to be submit. Later on, we are able to establish a collection of comprehensive medical analysis methods for Chinese patent medicine in collaboration with relevant nationwide medicine decision-making departments and administration divisions. It is believed that such cooperation could advertise the total implementation of the re-evaluation for Chinese patent medicine.The consistency of high quality on Chinese patent medicines is a hotspot and difficulty within the control of conventional Chinese medication preparations, and has become one of the bottlenecks restricting its internationalization. centered on the evaluation of current researches on high quality and problems of Chinese patent medicines, this report explored relevant ways of quality analysis on Chinese patent medications and possible elements affecting the consistency of quality into the pharmaceutical period by consulting appropriate literatures about quality analysis methods and persistence control practices of large-scale Chinese patent drugs. And it also submit the assessment system on top-notch Chinese patent medicines with "consistency" as the core, in order to market the entire enhancement regarding the quality of Chinese patent drugs, guide the rational cost of Chinese patent medicines of the same species, and supply a new reference design for the product quality assessment of Chinese patent drug.This research would be to explore the result of Qingfei Paidu Decoction(QPD) from the number metabolism and instinct microbiome of rats with metabolomics and 16 S rDNA sequencing. Based on 16 S rDNA sequencing of instinct microbiome and metabolomics(GC-MS and LC-MS/MS), we methodically studied the serum metabolites profile and gut microbiota composition of rats treated with QPD for continued 5 days by oral gavage. An overall total of 23 and 43 differential metabolites were identified according to QPD with GC-MS and LC-MS/MS, respectively. The involved metabolic paths of these differential metabolites included glycerophospholipid metabolic rate, linoleic acid k-calorie burning, TCA cycle and pyruvate metabolism. Meanwhile, we discovered that QPD dramatically regulated the structure of instinct microbiota in rats, such enriched Romboutsia, Turicibacter, and Clostridium_sensu_stricto_1, and reduced norank_f_Lachnospiraceae. Our existing study suggested that temporary input of QPD could significantly manage the host metabolism and gut microbiota structure of rats dose-dependently, recommending that the medical efficacy of QPD might be related to the legislation on host metabolic rate and gut microbiome.The purpose of this report was to explore the result of Schizonepetae Herba and Saposhnikoviae Radix(wind medication) on the phrase of AQP4 and AQP8 in colonic mucosa in rats with ulcerative colitis(UC). A total of 35 healthy SD male rats had been randomly split into regular group(gavaged with regular saline), DSS design team, along with low, center, and high dose wind medication groups(Schizonepeta and Saposhnikovia 1∶1, gavaged at dosages of 6, 12, and 24 g·kg~(-1)·d~(-1)), with 7 in each team. UC rat model had been founded by free consuming of 3% dextran sulphate sodium(DSS) answer for 10 times. At the end of the 10 th day following the treatment, mice had been put to demise to get colonic mucosa. The size of colon was calculated; the colonic mucosal injury index(CMDI) and pathological modifications of colon had been seen. ELISA technique was useful for calculating the content of serum IL-1, IL-8, and immunohistochemical strategy had been used to determine AQP4, AQP8 protein expressions in colon mucosa. The expressions of AQP4, AQP8 mRNAe signs and symptoms and histopathology of UC design rats and speed up the abdominal mucosal recovery. The method can be related to up-regulating the expression standard of AQP4 and AQP8 in colonic mucosa.The purpose of this paper was to explore the effect of Dingkun Dan on endometrial receptivity in rats with several lesions. Forty SD female rats with regular sexual pattern had been randomly split into 5 teams, control group, design group, progynova team, Dingkun Dan team and combination team. The slim endometrium model of cellular structural biology kidney-yang deficiency was created in all of those other rats except regular control group. The rats in normal control team had been free to eat and drink; the rats into the model team had been administered with distilled water; the rats when you look at the progynova group had been treated with progynova; rats in Dingkun Dan team had been addressed with Dingkun Dan, additionally the rats in combo group were treated with Dingkun Dan and progynova. After 15 days, serum degrees of OPN, VEGF and MMP-9 had been measured by ELISA. HE staining, immunohistochemistry and RT-PCR were used to evaluate endome-trial morphology, endometrial depth while the therapy system of Dingkun Dan. In comparison aided by the control group, the serum levelodel group(P<0.05), while VEGF mRNA phrase was decreased(P<0.05). As compared with the design group, MMP-9 mRNA phrase had been reduced somewhat when you look at the progynova group while the combo group(P<0.05). Dingkun Dan along with progynova can improve endometrial receptivity by up-regulating phrase of β-catenin, VEGF mRNA and down-regulating the expression of MMP-9 mRNA when you look at the damage rats.Curcumin had been made use of to restrict intense pancreatitis design rats to explore its potential procedure.