Immunohistochemical staining revealed the presence of albumin and increased microvessel density in the

vascular walls of atherosclerotic rabbits.

Conclusion: These results suggest that gadofosveset can be used to differentiate between atherosclerotic and normal rabbit vessel walls. (c) RSNA, 2009″
“Static and dynamic magnetic properties of oleic acid/oleyamine coated Mn-Zn ferrite nanoparticles of diameter 82 angstrom are reported. The zero-field-cooled peak temperature decreases with increasing magnetic field and obeys the well known de Almeida-Thouless line. AZD6094 datasheet The zero-field-cooled magnetization data are simulated by assuming noninteracting magnetic particles with uniaxial anisotropy and lognormal particle size distribution. The

relevant parameters give the values of particle diameter (D) 80 angstrom, standard deviation 0.3 in ln(D), and the anisotropy constant K to be 5.8 x 10(5) erg/cm(3). The observed higher value of standard deviation is due to the interparticle interaction. The complex magnetic susceptibility was measured as a function of temperature selleck kinase inhibitor for frequencies ranging from 67 to 1800 Hz. The temperature at which the maximum in the ac-susceptibility curve is observed is well accounted by the Vogel-Fulcher law for both chi’ and chi ”. The peak is also observed in a plot of chi ”/chi’ versus temperature, which may mean the existence of magnetic aftereffect, and furthermore, it has an Arrhenius as well as Vogel-Fulcher law type dependence. An observed nonthermal activation type relaxation mechanism at 12 K is attributed to possible quantum tunneling effect in Mn-Zn ferrite nanoparticles. (C) 2010 American Institute of Physics. [doi:10.1063/1.3310807]“
“The pilosebaceous unit is a complex structure that undergoes a specific growth cycle and comprises a few important drug targeting sites. For example, this website drugs can be targeted to the bulge region with stern cells or to the sebaceous glands. Interest in pilosebaceous units is directed towards their utilization as reservoirs for localized

therapy and also as a transport pathway for systemic drug delivery. Improved investigative methods, such as differential stripping, are being developed in order to determine follicular penetration. This article reviews relevant aspects of effective follicle-targeting formulations and delivery systems as well as the activity status of hair follicles, and variations in follicle size and distribution throughout various body regions. Each of these factors strongly affects follicular permeation. We provide examples of improved penetration of particle-based formulations and of a size-dependent manner of follicular penetration. Contradictions are also discussed, indicating the need for detailed future investigations. (C) 2009 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.