J Bacteriol 2002, 184: 5479–5490.PubMedCrossRef 3. Hughes AL, Friedman R, Murray M: Genomewide pattern of synonymous nucleotide substitution in two complete genomes of Mycobacterium tuberculosis . Emerg Infect Dis 2002, 8: 1342–1346.PubMed 4. Gao Q, Kripke KE, Saldanha AJ, Yan W, Holmes S, Small PM: Gene expression diversity among Mycobacterium tuberculosis clinical isolates. Microbiology 2005, 151: 5–14.PubMedCrossRef
5. Domenech P, Boshoff HI, Reed MB, Manca C, Kaplan G, Barry CE III: In vivo phenotypic dominance in mouse mixed infections with Mycobacterium tuberculosis clinical isolates. J Infect Dis 2005, 192: 600–606.PubMedCrossRef 6. Manca C, Tsenova L, Bergtold A, Freeman S, Tovey M, Musser JM, Barry CE III, Freedman
VH, Kaplan G: Virulence of a Mycobacterium Seliciclib cost tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta. Proc Natl Acad Sci USA 2001, 98: 5752–5757.PubMedCrossRef 7. Bellamy R, Ruwende selleck chemicals llc C, Corrah T, McAdam KP, Whittle HC, Hill AV: Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 1998, 338: 640–644.PubMedCrossRef 8. Weiss RA, McMichael AJ: Social and environmental risk factors in the emergence of infectious diseases. Nat Med 2004, 10: S70-S76.PubMedCrossRef 9. Kumar A, Bose M, Brahmachari V: Analysis of expression profile of mammalian cell entry ( mce ) operons of Mycobacterium tuberculosis . Infect Immun 2003, 71: 6083–6087.PubMedCrossRef 10. Aguilar LD, Infante E, Bianco MV, Cataldi A, Bigi F, Pando RH: Immunogenicity and protection induced by Mycobacterium tuberculosis mce-2 and mce-3 mutants in a Balb/c mouse model of progressive pulmonary tuberculosis. Vaccine 2006, 24: 2333–2342.PubMedCrossRef 11. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher
C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE III, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares Mephenoxalone S, Sulston JE, Taylor K, Whitehead S, Barrell BG: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998, 393: 537–544.PubMedCrossRef 12. Sassetti CM, Rubin EJ: Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci USA 2003, 100: 12989–12994.PubMedCrossRef 13. Ahmad S, Akbar PK, Wiker HG, Harboe M, Mustafa AS: Cloning, expression and immunological reactivity of two mammalian cell entry proteins encoded by the mce1 operon of Mycobacterium tuberculosis . Scand J Immunol 1999, 50: 510–518.PubMedCrossRef 14.