These findings differ from studies with drug users in Poland [9] and Siberia [28], which recorded association between dental procedures and HCV genotype 1. But it agrees with a study from Lybia that recorded neither high incidence of the genotype 2 after surgery and dental procedure [29].HCV genotype is a predictive factor to antiviral treatment response. There are clear evidence [30] indicating that genotypes 1 and 4 are associated to poor interferon response, either in single therapy or combined with ribavirin, the opposite being true for genotypes 2 and 3 treated for 24 weeks. Best treatment results, measured by viral parameters, are reached within 48 weeks for patients with genotype 2 or 3, while patients with genotype 1 need one year of treatment.

Therefore, long-term benefits of HCV treatment may be estimated based on the characteristics of the treated population.Since HCV treatment has high costs and is provided by the public health care system for all Brazilian citizens, we believe that almost all HCV positive patients from that regional population were included in the studied sample, but they may be representative of the lower income population. Although disease register is mandatory, occasionally the form was incompletely filled, causing loss of epidemiologic information and a limitation of our study. The method limitation to identify genotype subtypes deserves mention, but this was not an aim of the study and it is still the method performed in the Brazilian health system and the only one offered by the public system, in the place where the study was conducted.

In conclusion, in a region from south Brazil the most common HCV genotype was type 1, followed by type 3, in accordance to previous reports, but the proportion of genotype 2 was higher than expected and was significantly associated to history of dental procedures and older age.Conflict of InterestsThe authors report no commercial association or any other potential Batimastat conflict of interests.Ethical ApprovalEthical approval was gained from Ethics Committee of Passo Fundo University.
Nocturnal habits, relatively secure roosting locations, and the ability to fly and produce ultrasonic sounds have allowed many species of microchiropteran bats to evolve an extensive and sophisticated system of acoustic social communication without the fear of being detected by predators [1, 2]. In most instances, these same behavioral characteristics also make it difficult to study their audiovocal communication behavior.