2008 S165 0644 agitation in intensive care: description of the incidence and risk factors associated with A. Sandiumenge1, Mr. Jime nez2, C. Chamorro3, C Pardo4, T. �� OZ5 Mun, J. Alonso6, H. Torrado7, Mr. Alonso8 1ICM that h Capital Universit t Joan Vismodegib 879085-55-9 XXIII, Tarragona, 2ICM, University Hospital Clinico San Carlos, 3ICM, the H Pital Universit t Puerta de Hierro, 4ICM, the h Capital Universit t Fuenlabrada, Madrid, 5ICM, H Pital Txagorritxu, Vitoria, 6ICM, the h Capital Universit t d0Hebron Vall, 7ICM, Bellvitge University Hospital, Barcelona 8ICM, the h Capital Universit t 12 de Octubre, Madrid, Spain Introduction. To reduce the incidence and agitation factors, to describe associated with its development in the ICU. METHODS.
All patients in the ICU Spanish 9 (1 doctor, 1 surgery, 1 and 6 medical and surgical trauma w During a period of 30 days were followed until death or discharge. Age, gender, were the history of alcohol and illegal drugs recorded at admission. admission diagnosis, APACHEII, length of stay in ICU (ALOS and mortality t and critical care GSK1904529A 1089283-49-7 (mechanical ventilation (MV and sedation / analgesia (SA were also recorded. Pr presence of agitation for clinical evaluation of intensive care, for the patient was diagnosed. Statistical analysis was performed using SPSS 13.0. significance level of p \ 0, 05 were RESULTS. A total of 471 patients (66.9% M men, mean age 58.917.6 y / o were for medical reasons (52 , 2% postoperatively (38.4% approved or traumatic (7, 4% of the cause, with an average of APACHEII 13.28.3 (range 0 44 Seventy-nine (16.7%, and 21 patients (4.
4% had a history of alcohol and drug abuse respectively. mean ICU LOS was 138.5199.0 hours (between 1 and 1604. Two hundred and 44 patients (51.8% were mechanically for an average of 190.7 hours 114.7 and 227 (48.2% ventilated have again u stored continuous sedation and / or analgesia (mean time 88.5128.6 and 132.1187.0 hours. Fifty-eight (12.3% of patients did not survive the ICU. agitation incidence was 07/26/1000 ICU days (N70 and was at an average of 70.3103.5 hours after admission to the ICU diagnosed. agitated patients had longer ICU LOS (260.2291.6 107.9157.6 drawbacks, p \ 0.001, duration of MV (190.6227.2 73.9136.0 against, p \ 0.001 and the sedation period (59.598.5 118.6161.1 disadvantages, p \ 0.012 rather than shaken. history of alcohol abuse (p0.
001, time to sedation (p0 0083 and the use of midazolam (p0.001, propofol (p0.001 , morphine hydrochloride (p0.004 or fentanyl (p0.03 are stirring in the one-dimensional analysis associated with a fwd rts-regression multivariable model history of alcohol abuse (3.45, 95% CI:. 1 48 to 8.01 and Sedo analgesia with midazolam (3.29 or 95% CI 1.42 to 7.64 profofol (OR 5.79, 95% CI: 2.42 to 13.89, or fentanyl (OR 2 87, 95% CI 2.1 to 8.7 were identified as factors independently Independent Press predictors for excitement. (Hosmer and Lemshow test p0.36. CONCLUSION. agitation is an hour INDICATIVE complication in critically ill patients. Its Development can zusammenh to patient characteristics, lengths, but also in intensive care interventions such that the practice of sedation and analgesia, factors associated with an increased Hten mortality 0645 IN PATIENTS WITH ALI / ARDS receiving mechanical ventilation.
A multivariate analysis of V. Tomicic PP Vargas Ugarte CC, SS Sun, Kirsten KK, AA Fuentealba, RR Moreno Delgado II EE Mart nose, DC Canals UPC Clinica Alemana of Santiago, Facultad de Medicina Universidad del Desarrollo Clinica Alemana, Santiago, Chile. INTRODUCTION The results of the ALI / ARDS patients can relate to different factors may be due. Several severity gamble walls and gas exchange parameters were as Pr predictors for mortality t in these patients is proposed. The oxygenation index (OI was in big em style in the field of pediatrics used, but it is not always in the intensive care units for adults (ICU.
Our objective was to evaluate the pr predictive variables, including normal early as Pr OI predictor of mortality t in ALI or ARDS patients mechanical ventilation underwent resist (mean MV .. Methods All consecutive patients, the MV whose PaO2/FiO2 ratio ratio at admission was less than 300 mmHg were between September 2006 and September 2007 included. The age, APACHE II, SOFA gas exchange, respiratory, PEEP pressure were obtained. PaO 2 / FiO 2 and OI were calculated. These indicators may need during the first 48 hours were identified. mortality t was admitted to the intensive care unit. Numerical variables were compared with Mann-Whitney U-test. defined in univariate analysis, the risk of mortality between different variables. significant variables (p \ 0.05 were included in a logistic regression analysis several steps Rev rts.
results using odds ratio (OR 95% CI RESULTS hundred and 21 patients were examined Age, APACHE II and SOFA were as follows: … .. 6418, 207, and 8.53.4 or ICU overall mortality was 11% t Major factors were associated independently of one another with an increased mortality Hten t: OI On the second day (OR 3.4, 95% CI: 1.06 10.96, p0.04, PaCO 2 on the second day (OR = 1.4, 95% CI, 1.05 1.83, P0.02, APACHE II at admission (OR 1.23, 95%