We derive analytical approximations for the ISI density and ISI serial correlation coefficient for both cases. For fast fluctuations and deterministic adaptation, the ISI density is well approximated by an inverse Gaussian (IG) and the ISI correlations are negative. In marked contrast, for stochastic adaptation, the density is more peaked and has a heavier tail than an IG density and the serial correlations are positive. A numerical study of the mixed case where both fast fluctuations and adaptation channel noise are present reveals a
smooth transition between the analytically tractable limiting cases. Our conclusions are furthermore supported by numerical simulations of a biophysically more realistic Hodgkin-Huxley type model. Our results could be used to infer the dominant
source of noise Dinaciclib in neurons from their ISI statistics.”
“Self-assembled Pt nanostructures, which are formed by evaporation and subsequent diffusion limited aggregation of Pt on graphite, have been studied by photoemission and scanning electron microscopy. Adsorption of CO has been studied by temperature programmed desorption. Charge induced Pt 4f core level shifts in the order of 1 eV that depend on the effective dimensions of the nanostructures have been observed, and effective dimensions of the Pt structures have been defined based on the Pt 4f core level shifts. The effective dimensions of the Pt structures have been correlated with changes in the thermal desorption of adsorbed CO. It is observed that smaller effective dimensions in the few nanometer range result in lower desorption temperatures of up to 50 K. The possible role of hot electrons CCI-779 cell line CUDC-907 in the adsorption process has been discussed. (C) 2011 American Institute of Physics. [doi:10.1063/1.3596572]“
“We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and
HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples of 399 women, received for routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive specimens were typed by RFLP. A structured epidemiological questionnaire was administered to each woman. HPV prevalence among these cytologically normal women was 11%. Twelve viral types were detected, the most common being HPV-16, -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral types were detected in 61% of the infected women and 27% of the infected women had multiple HPV infections. Significant associations of HPV infection were found with age, literacy, residence, marital status, lifetime number of sexual partners, and parity. We detected a great diversity of HPV types in women with normal cytology.